Thammadul Wellness Center is a health and wellness center focused on restoring balance to the body and mind through natural therapy and holistic care. Designed as a retreat for relaxation and rejuvenation, the center integrates alternative medicine, nutritional therapy, appropriate exercise, and an environment that promotes tranquility. The center offers a wide range of services, including Thai herbal spa treatments, yoga and meditation, nutritional counseling, and personalized health restoration programs. The architectural design emphasizes the use of natural materials and a setting that harmonizes with the surrounding environment, creating a serene atmosphere that allows visitors to reconnect with nature. Thammadul Wellness Center aims to promote the concept of holistic health care, emphasizing prevention rather than treatment, so that guests can adopt these wellness practices into their daily lives sustainably.
1.ความเครียดและปัญหาสุขภาพจากวิถีชีวิตสมัยใหม่ 2.อนุรักษ์และส่งเสริมภูมิปัญญาท้องถิ่นด้านสุขภาพ 3.ให้ความสำคัญกับการดูแลสุขภาพเชิงป้องกันมากขึ้น ทำให้แนวทางธรรมชาติบำบัดได้รับความนิยม
คณะทันตแพทยศาสตร์
Objective or Background: Dental caries is still one of the most significant dental problems worldwide, with prevalence rates up to 90% among children and adults. Cariogenic bacteria, especially Streptococcus mutans, is the primary microorganism involved in the pathogenesis through carbohydrate metabolism and biofilm formation, which are challenging to eradicate. Histatin-5 (HST-5), a human salivary antimicrobial peptide, has demonstrated antimicrobial activity against various fungal and bacterial pathogens. Phytosphingosine (PHS), an endogenous bioactive sphingolipid found in fungi, plants, and humans, also shows antimicrobial properties. This study aimed to evaluate the killing activity of HST-5 alone and in combination with PHS against S. mutans under biofilm-stimulating conditions. Materials and Methods: Antimicrobial activity against a planktonic culture of S. mutans was evaluated using a time-kill assay, and biofilm-forming capacity was confirmed by crystal violet staining assay. The killing ability against 24h pre-formed biofilm was determined using Transferable Solid Phase (TSP) pin lid model. Synergistic activity between HST-5 and PHS was evaluated using the checkerboard technique. Additionally, the cytotoxicity of the tested agent on human gingival fibroblast cells (hGFs) was assessed after 1 h of incubation using an MTT assay. Results: A time-kill assay revealed that both HST-5 and PHS exhibit time- and concentration-dependent activity against the planktonic form of S. mutans. PHS achieved over 90% killing activity within 15 min at 5 μg/ml, whereas HST-5 required 30 min to reach 90% killing at 20 μM. The biofilm formation capacity of S. mutans was confirmed. The inhibitory concentrations (IC50) of HST-5 and PHS against S. mutans biofilm were 25 μM and 13.5 μg/ml, respectively. A synergistic interaction between HST-5 and PHS, with IC50 values reduced by 8-fold and 16-fold, respectively. No cytotoxic effects were observed in hGFs cells at the concentration of the synergistic interaction. Conclusions: Therefore, the combination of HST-5 and PHS may enhance the effectiveness of anti-infective agents against S. mutans biofilm, potentially preventing the development of dental caries.
วิทยาเขตชุมพรเขตรอุดมศักดิ์
Abstract: Banana French Fries This project aimed to study and develop the product Banana French Fries, which is a snack made by frying bananas in a form similar to French fries, in order to add value to bananas and create new choices for consumers. The experiment consisted of selecting suitable banana varieties, developing a coating formula, and testing the taste of samples. The results of the study found that Nam Wa bananas are the most suitable for making banana French fries because they have a firm texture and naturally sweet taste. The best coating formula consists of wheat flour, eggs, and milk, which provide longer crispiness. The taste test found that most consumers gave a very good response and were satisfied with the taste and texture. This project shows that banana French fries are a product with potential to be developed as a healthy snack and can be further developed into a commercial product in the future.
วิทยาลัยการจัดการนวัตกรรมและอุตสาหกรรม
The Water Hyacinth Removal Electric Smart Boat is a small, streamlined boat capable of working in any area. Even small areas with a lot of water hyacinth volumes with advanced technology that the researcher has created and designed. The structure of the boat is made of aluminum material, is 4.80 meters long and 1.20 meters wide, and is powered by a diesel engine 14 hp. Reinforcing drive in tandem with spinning, chopping weeds and the ability to remove water hyacinths by spinning 3-5 per day with only one operator on boat. Therefore, the control and removal of water hyacinths by smart boat works better than conventional mechanization. It can work quickly and at a low cost. This water hyacinth removal electric smart boat concept will be built on the original system.