Bone tissue scaffolds are made from biomaterials that support rapid repair and healing. Scaffold fabricators have produced materials that are able to degrade a biosystem or human body excellently. Thus, this work aims to study the optimization of materials, shape, and the 3D printing process with FDM. Finite element analysis is also used to predict mechanical properties of the scaffold and find the optimal shape and pore size. However, the materials studied include PLA, PCL, and HA.
โครงเลี้ยงเซลล์ (Scaffold) หรือวัสดุที่มีรูพรุนเพื่อการเจริญเติบโตของเซลล์สู่การกลายเป็นเนื้อเยื่อสำหรับการฟื้นฟูส่วนที่เสียหายของร่างกาย ซึ่งในปัจจุบันมีความเสียหายของเนื้อเยื่อที่เกิดขึ้นจากอุบัติเหตุ โรค เป็นต้น โดยการรักษาแบบดั้งเดิมจะใช้การรับเนื้อเยื่อจากผู้บริจาค แต่ก็อาจไม่เข้ากันกับร่างกายของผู้ป่วยทางวิศวกรรมเนื้อเยื่อจึงได้มีการพัฒนาโครงเลี้ยงเซลล์ขึ้นมาซึ่งจำเป็นต้องมีคุณสมบัติที่สำคัญ ได้แก่ การทนต่อการรับแรง การย่อยสลายภายในร่างกาย และความเข้ากันได้ทางระบบชีวภาพ อย่างไรก็ตามมีความท้าทายมากมายในการพัฒนาวัสดุชีวภาพในโครงเลี้ยงเซลล์ เช่น การรองรับความหนาแน่นของเซลล์ที่เพิ่มขึ้นเนื่องจากการเจริญเติบโต ซึ่งจำเป็นต้องออกแบบรูพรุนภายในโครงเลี้ยงเซลล์ การรับแรงการแรงกดโดยมวลกล้มเนื้อของร่างกาย และเลือกวัสดุที่เหมาะสมเพื่อรองรับการเจริญเติบโตของเซลล์ เป็นต้น
คณะสถาปัตยกรรม ศิลปะและการออกแบบ
This study aims to identify the toothbrush appearance factors that affect baby boomers purchasing decisions. The research divide into three stages: The first stage is to classify the toothbrush appearance factors through a review of literature, research, and examining toothbrushes currently available on the market, summarizing them as appearance factors. The second stage is to summarize the results of the toothbrush appearance factors to create a multiple-choice questionnaire in three dimensions: purchasing decisions, aesthetics, and functionality. Collecting data from a group of 30 Baby Boomers aged 57-75 years old. The last stage is to summarize the three dimensions of appearance factors affecting baby boomers' toothbrush purchasing decisions and report as percentages and rank them. The research findings indicate that the most significant toothbrush appearance factor is a "Curved handle," accounting for 80%, followed by “Multi-level bristles” at 70%, a "Rubber thumb rest" at 53.3%, "Handle divided into more than two parts" at 50%, and “Offset shape” at 40%, respectively. In terms of the reason for purchasing decision based on various factors are as follows: the curved handle and offset shape give a sense of purchase with its aesthetic, While the selection of multi-level bristles, the Rubber thumb rest, and the handle divided into more than two parts due to functionality.
วิทยาลัยการจัดการนวัตกรรมและอุตสาหกรรม
Diabetes is a significant global health issue, particularly due to complications related to diabetic wounds. Studies indicate that approximately 15-25% of diabetic patients develop foot ulcers, with more than 50% of severe cases leading to amputation. This results in a substantial decline in the quality of life for patients. Current treatments for diabetic wounds face challenges such as antibiotic-resistant bacterial infections and delayed wound healing, highlighting the need for innovative solutions to accelerate the healing process and reduce the risk of limb loss. Cotylelobium lanceolatum Craib, a medicinal plant long utilized in traditional Thai medicine, is known for its anti-inflammatory and wound-healing properties. This study focuses on developing an extract from Cotylelobium lanceolatum Craib in the form of nano silver (Nano Silver) to enhance the effectiveness of diabetic wound treatment. Nano silver technology enables deeper penetration into the skin, provides potent antibacterial activity, and promotes wound healing by reducing inflammation and stimulating tissue regeneration. The development of nano silver derived from Cotylelobium lanceolatum Craib extract is expected to help reduce chronic wounds in diabetic patients, lower the risk of infection, and decrease the incidence of limb amputation and mortality associated with diabetic wound complications. This research represents a significant step toward creating a safer and more effective treatment alternative for diabetic wound care.
คณะวิทยาศาสตร์
Otitis Media is an infection of the middle ear that can occur in individuals of all ages. Diagnosis typically involves analyzing images taken with an otoscope by specialized physicians, which relies heavily on medical experience to expedite the process. This research introduces computer vision technology to assist in the preliminary diagnosis, aiding expert decision-making. By utilizing deep learning techniques and convolutional neural networks, specifically the YOLOv8 and Inception v3 architectures, the study aims to classify the disease and its five characteristics used by physicians: color, transparency, fluid, retraction, and perforation. Additionally, image segmentation and classification methods were employed to analyze and predict the types of Otitis Media, which are categorized into four types: Otitis Media with Effusion, Acute Otitis Media with Effusion, Perforation, and Normal. Experimental results indicate that the classification model performs moderately well in directly classifying Otitis Media, with an accuracy of 65.7%, a recall of 65.7%, and a precision of 67.6%. Moreover, the model provides the best results for classifying the perforation characteristic, with an accuracy of 91.8%, a recall of 91.8%, and a precision of 92.1%. In contrast, the classification model that incorporates image segmentation techniques achieved the best overall performance, with an mAP50-95 of 79.63%, a recall of 100%, and a precision of 99.8%. However, this model has not yet been tested for classifying the different types of Otitis Media.