This research aims to optimize the production process of gamma-aminobutyric acid (GABA) in fermented pineapple juice using probiotics and acetic acid bacteria (AAB), which are microorganisms with the potential to enhance GABA levels. This process has been developed to improve the nutritional value of fermented pineapple juice and to increase the economic value of Thai pineapples, which have long suffered from low market prices. This study focuses on determining the optimal conditions for GABA production by examining factors such as sugar content, pH levels, fermentation duration, and L-glutamate concentration, as well as the co-cultivation of probiotics and acetic acid bacteria. The experiments are conducted using controlled fermentation techniques, and the bioactive components of the fermented juice are analyzed with advanced instruments such as HPLC and GC-MS. The findings of this research are expected to contribute to the development of formulations and production processes for a high-GABA pineapple-based functional beverage. This product could offer health benefits such as stress reduction, cognitive function enhancement, and relaxation while also strengthening the potential of Thailand’s fermented food and beverage industry.
การพัฒนากระบวนการผลิตกรดแกมมา-อะมิโนบิวทิริก (γ -aminobutyric acid) ในเครื่องดื่มจากน้ำสับปะรดด้วยโพรไบโอติกซึ่งเน้นการใช้แบคทีเรียกรดอะซิติกและโพรไบโอติกเพื่อเพิ่มประสิทธิภาพการผลิต GABA โดยที่มาของการวิจัยนี้เกิดจากความต้องการแก้ไขปัญหาราคาสับปะรดของไทยซึ่งมีราคาต่ำมาเป็นเวลานาน การผลิตเครื่องดื่มที่มี GABA สูง มีประโยชน์ต่อสุขภาพ เช่น ช่วยในการผ่อนคลาย ลดความวิตกกังวล และส่งเสริมการทำงานของสมอง
คณะทันตแพทยศาสตร์
Aggregatibacter actinomycetemcomitans is a key pathogen in periodontal disease, damaging periodontal ligaments and alveolar bone through biofilm formation. D-LL-31, an engineered antimicrobial peptide, exhibits superior biofilm-killing ability compared to conventional treatments, while DNase I enhances its efficacy by disrupting the biofilm matrix. This study evaluated the combined effects of D-LL-31 and DNase I on A. actinomycetemcomitans biofilms. Results showed that D-LL-31 effectively eradicated biofilms, and its combination with DNase I further enhanced biofilm disruption without cytotoxicity to gingival epithelial cells. The D-LL-31 and DNase I combination shows potential for development as a mouthwash to improve oral health and combat periodontal disease.
คณะเทคโนโลยีการเกษตร
This project presents a design and management approach for agricultural land in Kanchanaburi Province. The case study area is situated in Wangdong Subdistrict, Mueang Kanchanaburi District, covering an area of approximately 18 rai (7.2 acres). As the user seeks a simplified lifestyle in the countryside, surrounded by nature, the design aligns with this vision of simplicity and sustainability. The land is systematically allocated to optimize the benefits for both daily living and agricultural industry development. The crop cultivation zones are designed to suit the local climate and plant varieties, ensuring high-quality yields for continuous utilization. Meanwhile, the livestock zones are clearly delineated to maintain balance and organization. This approach not only ensures food security and income generation but also promotes a lifestyle that harmonizes with nature, minimizes environmental impact, and supports the long-term development of an efficient and eco-friendly agricultural industry. Comprehensive attention is given to the positioning of various zones, considering wind direction and sunlight exposure. Additionally, the design undergoes a rigorous drafting and review process to ensure the optimal outcomes for the land's utilization.
คณะเทคโนโลยีการเกษตร
Public Park Project: Coastal folk Park is a design park in the area of Ang Sila Subdistrict, Chonburi Province. In an area of 22 acre, it is intended to be a place of rest, recreation, and also a source of learning and conservation of the seashore and the traditional way of life of the area.